SCHEMBL2833024

SCHEMBL2833024

Oc1c(Cl)cc(C(F)(c2cc(Cl)c(O)c(Cl)c2)C(F)(F)C(F)(F)F)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.42
TSHR P16473 5/20 0.42
TTR P02766 3/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 3/20 0.42
RECQL P46063 3/20 0.42
THRB P10828 3/20 0.39
ALOX15 P16050 3/20 0.38
ALOX12 P18054 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HIF1A Q16665 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 4/20 0.34
MAPK1 P28482 3/20 0.34
CASP1 P29466 2/20 0.32
NR1I2 O75469 2/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7029201 0.91 MEN1 (0.38) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL29185432 0.78 TSHR (0.43) HSD17B10TSHRHPGDNR1H2NR1H3
SCHEMBL6844032 0.77 HSD17B10 (0.46) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL5600053 0.77 ALDH1A1 (0.50) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL2837831 0.76 ESR1 (0.45) TTRALDH1A1CYP3A4CYP1A2CYP2C19
SCHEMBL542204 0.76 NR1H3 (0.44) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL28226604 0.72 HSD17B10 (0.41) HSD17B10TSHRTTRALDH1A1CYP3A4
SCHEMBL28429812 0.71 KLF10 (0.36) ALOX15CYP2C19MAPK1HTTKDM4E
SCHEMBL28235804 0.70
SCHEMBL4457086 0.67 HSD17B10 (0.50) HSD17B10TSHRTTRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116144029-A Organosilicon leveling agent, preparation method thereof, black matrix photosensitive resin composition, color filter and liquid crystal display device 阜阳欣奕华材料科技有限公司 2023-05-23 CN claimed
CN-109634056-B Photosensitive resin composition and method for producing substrate with resin film 日铁化学材料株式会社 2024-07-09 CN disclosed
CN-118259550-A Photosensitive resin composition, cured film, color filter, touch panel, and display device 日铁化学材料株式会社 2024-06-28 CN disclosed
CN-117991589-A Photosensitive resin composition for black resist, light shielding film, color filter, touch panel, and display device 日铁化学材料株式会社 2024-05-07 CN disclosed
CN-117820197-A Oxime ester initiator, black matrix photosensitive resin composition containing oxime ester initiator and application of black matrix photosensitive resin composition 阜阳欣奕华材料科技有限公司 2024-04-05 CN disclosed
CN-108693704-B Photosensitive resin composition, light shielding film, liquid crystal display device, and method for manufacturing light shielding film and liquid crystal display device 日铁化学材料株式会社 2024-03-26 CN disclosed
CN-117192898-A Photosensitive resin composition, cured film, display component, and display device 日铁化学材料株式会社 2023-12-08 CN disclosed
CN-116954023-A Negative photosensitive resin composition, cured film, and pattern cured film 武汉柔显科技股份有限公司 2023-10-27 CN disclosed
CN-116893573-A Photosensitive resin composition, cured film, substrate with cured film, and method for producing substrate with cured film 日铁化学材料株式会社 2023-10-17 CN disclosed
CN-116893574-A Substrate with cured film, photosensitive resin composition, method for producing substrate with cured film, and display device 日铁化学材料株式会社 2023-10-17 CN disclosed
US-20080090177-A1 Resin Composition Comprising Cardo Resin, Method for Forming Pattern Using the Resin Composition and Color Filter Using Pattern Formed by the Method CHEIL INDUSTRIES INC. (KR) 2008-04-17 US disclosed
US-20060102051-A1 Photosensitive resin composition and curing product thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-05-18 US disclosed
WO-2006046733-A1 THIOL COMPOUND, AND PHOTOSENSITIVE COMPOSITION AND BLACK MATRIX RESIST COMPOSITION USING THE COMPOUND SHOWA DENKO K.K (JP) 2006-05-04 WO disclosed
EP-1600812-A1 PHOTOSENSITIVE RESIN COMPOSITION AND CURING PRODUCT THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2005-11-30 EP disclosed
US-6780549-B2 PHOTOPOLYMERIZABLE UNSATURATED COMPOUND, A COMPOUND CONTAINING AN EPOXY GROUP, A PHOTOPOLYMERIZATION INITIATOR OR SENSITIZER, AND A SILICA SOL FILLER WITH A DIAMETER OF BETWEEN 5 NM-0.5 MU M NIPPON STEEL CHEMICAL CO., LTD. (JP) 2004-08-24 US disclosed
US-20020051942-A1 Photo-or heat-curable resin composition and multilayer printed wiring board NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2002-05-02 US disclosed
EP-0646845-B1 COLOR FILTER, MATERIAL THEREOF AND RESIN NIPPON STEEL CORP (JP) 2001-03-14 EP disclosed
US-5721076-A A PHOTO OR THERMAL CURABLE, ALKALI-DEVELOPABLE PHOTOSENSITIVE POLYESTER MONOMERS CONTAINING ACRYLATED BISPHENOL EPOXY COMPOUNDS AND MONOANHYDIDE OR DIANHYDRIDE COMPOUNDS; NIPPON STEEL CORPORATION (JP) 1998-02-24 US disclosed
US-5710234-A POLYORTHOESTERS FOR MOLDING MATERIALS, ADHESIVES AND HEAT RESISTANT POLYMERS NIPPON STEEL CHEMICAL CO., LTD. (JP) 1998-01-20 US disclosed
EP-0646845-A1 COLOR FILTER, MATERIAL THEREOF AND RESIN Nippon Steel Corporation (JP) 1995-04-05 EP disclosed