SCHEMBL28227769

SCHEMBL28227769

O=S(=O)(c1ccccc1)c1ccc(S(=O)(=O)c2ccc(Br)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.70
CA2 P00918 3/20 0.52
IDO1 P14902 1/20 0.52
MAPT P10636 3/20 0.50
HTT P42858 2/20 0.50
LMNA P02545 1/20 0.50
PLCG1 P19174 1/20 0.50
ALDH1A1 P00352 4/20 0.49
TDP1 Q9NUW8 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
POLB P06746 1/20 0.47
MMP2 P08253 2/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
CA1 P00915 1/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16487 1.00 HTR6 (0.70) HTR6CA2IDO1MAPTHTT
SCHEMBL28582400 0.91 ALDH1A1 (0.59) HTR6CA2IDO1MAPTHTT
SCHEMBL250285 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL8978700 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL18187419 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL2122562 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL17739625 0.89 ALDH1A1 (0.65) HTR6CA2MAPTHTTLMNA
SCHEMBL11661221 0.88 HTT (0.62) HTR6CA2MAPTHTTLMNA
SCHEMBL5051390 0.87 HTR6 (0.93) HTR6CA2MAPTHTTLMNA
SCHEMBL18187421 0.86 ALDH1A1 (0.58) HTR6CA2MAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108148055-B D-pi-A type organic fluorescent material based on naphthalene and preparation method thereof 陕西师范大学 2021-04-13 CN disclosed
CN-108148055-A A kind of D- π-A types organic fluorescence materials and preparation method based on naphthalene 陕西师范大学 2018-06-12 CN disclosed