SCHEMBL16487

SCHEMBL16487

O=S(=O)(c1ccccc1)c1ccc(Br)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.70
CA2 P00918 3/20 0.52
IDO1 P14902 1/20 0.52
MAPT P10636 3/20 0.50
HTT P42858 2/20 0.50
LMNA P02545 1/20 0.50
PLCG1 P19174 1/20 0.50
ALDH1A1 P00352 4/20 0.49
TDP1 Q9NUW8 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
POLB P06746 1/20 0.47
MMP2 P08253 2/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
CA1 P00915 1/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28227769 1.00 HTR6 (0.70) HTR6CA2IDO1MAPTHTT
SCHEMBL28582400 0.91 ALDH1A1 (0.59) HTR6CA2IDO1MAPTHTT
SCHEMBL250285 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL8978700 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL18187419 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL2122562 0.89 CA2 (0.62) HTR6CA2IDO1MAPTHTT
SCHEMBL17739625 0.89 ALDH1A1 (0.65) HTR6CA2MAPTHTTLMNA
SCHEMBL11661221 0.88 HTT (0.62) HTR6CA2MAPTHTTLMNA
SCHEMBL5051390 0.87 HTR6 (0.93) HTR6CA2MAPTHTTLMNA
SCHEMBL18187421 0.86 ALDH1A1 (0.58) HTR6CA2MAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022262300-A1 NEUTRAL IRIDIUM COMPLEX CONTAINING BIPHENYL DERIVATIVE LIGAND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 江苏科技大学 2022-12-22 WO claimed
CN-113354689-B Neutral iridium complex containing biphenyl derivative coordination, preparation method and application thereof 江苏科技大学 2022-09-23 CN claimed
CN-114716376-A Derivative compound based on sulfone electron acceptor and preparation method and application thereof 广东工业大学 2022-07-08 CN claimed
CN-113354689-A Neutral iridium complex containing biphenyl derivative coordination, preparation method and application thereof 江苏科技大学 2021-09-07 CN claimed
US-10937971-B2 Organic monomolecular white light material, manufacturing method for the same, and OLED element SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2021-03-02 US claimed
US-20200295274-A1 ORGANIC MONOMOLECULAR WHITE LIGHT MATERIAL, MANUFACTURING METHOD FOR THE SAME, AND OLED ELEMENT SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2020-09-17 US claimed
CN-108148055-A A kind of D- π-A types organic fluorescence materials and preparation method based on naphthalene 陕西师范大学 2018-06-12 CN claimed
CN-108084150-A Organic supramolecular white light emitting material and preparation method thereof and OLED device 深圳市华星光电技术有限公司 2018-05-29 CN claimed
US-6165677-A Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-26 US claimed
US-20250099448-A1 HETEROCYCLIC COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-03-27 US disclosed
CN-114901638-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2024-10-29 CN disclosed
CN-114409701-B Diphenyl sulfone-based thermal excitation delayed fluorescence aromatic phosphine oxide material and its synthesis method and use 黑龙江大学 2024-05-31 CN disclosed
US-11981661-B2 Heterocyclic compounds HOFFMANN-LA ROCHE INC. (US) 2024-05-14 US disclosed
EP-3481831-B1 4-AMINOPYRAZOLO[3,4-D]PYRIMIDINYLAZABICYCLO DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO LTD (KR) 2023-09-06 EP disclosed
US-4603103-A THERMALLY DECOMPOSABLE ORGANIC SILVER SALT ON A SUPPORT FUJI PHOTO FILM CO., LTD. (JP) 1986-07-29 US disclosed
US-4554381-A BORON TRIFLUORIDE, HYDROFLUORIC ACID RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-11-19 US disclosed
EP-0160996-A2 Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-11-13 EP disclosed
EP-0143424-A2 Heat-developable light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1985-06-05 EP disclosed
US-4082793-A AROMATIC PHOSPHINIC ACIDS CONTAINING SULFONE LINKAGE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-04-04 US disclosed
US-4026830-A FILLERS USED IN HIGH TEMPERATURE LAMINATES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10937971-B2 Organic monomolecular white light material, manufacturing method for the same, and OLED element NLRP3, NLRP1, OCIAD1 HTR6 2489/4885CA2 4085/4885IDO1 1812/4885
US-11981661-B2 Heterocyclic compounds CBR3, BRIX1, CCNY HTR6 2393/4885CA2 3696/4885IDO1 1398/4885
US-20200295274-A1 ORGANIC MONOMOLECULAR WHITE LIGHT MATERIAL, MANUFACTURING METHOD FOR THE SAME, AND OLED ELEMENT NLRP3, NLRP1, OCIAD1 HTR6 2489/4885CA2 4085/4885IDO1 1812/4885
US-20250099448-A1 HETEROCYCLIC COMPOUNDS OPRM1, CYP1A1, CYP3A4 HTR6 535/4885CA2 4628/4885IDO1 805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.