Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837424 | 1.00 | CYP1A2 (0.38) | CYP1A2CYP2C19PTPN1CCNCCDK8 | |
| SCHEMBL30560977 | 0.78 | PTPN1 (0.40) | PTPN1CCNCCDK8IAPPPTGER1 | |
| SCHEMBL1124329 | 0.78 | ALDH1A1 (0.48) | CYP1A2PTPN1CCNCCDK8LMNA | |
| SCHEMBL28358892 | 0.78 | ALDH1A1 (0.48) | CYP1A2PTPN1CCNCCDK8LMNA | |
| SCHEMBL1124331 | 0.78 | ALDH1A1 (0.48) | CYP1A2PTPN1CCNCCDK8LMNA | |
| SCHEMBL30560932 | 0.78 | ALDH1A1 (0.48) | CYP1A2PTPN1CCNCCDK8LMNA | |
| SCHEMBL8415411 | 0.78 | PTPN1 (0.41) | PTPN1CCNCCDK8PTGER1PTGER4 | |
| SCHEMBL8415409 | 0.78 | PTPN1 (0.41) | PTPN1CCNCCDK8PTGER1PTGER4 | |
| SCHEMBL28229070 | 0.77 | PTGER3 (0.42) | PTPN1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL17095076 | 0.77 | CD44 (0.41) | PTPN1CCNCCDK8IAPPPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |