SCHEMBL28229403

SCHEMBL28229403

O=C1Cc2ccccc2OC1CO

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.39
MAOB P27338 6/20 0.39
ANPEP P15144 6/20 0.37
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
AOC2 O75106 5/20 0.35
DAO P14920 1/20 0.35
TSHR P16473 1/20 0.35
STK17B O94768 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27569347 0.81 ANPEP (0.42) MAOAMAOBANPEPNISCHAOC2
SCHEMBL27347568 0.80 MAOB (0.37) MAOAMAOBANPEPHPGDALDH1A1
SCHEMBL28904739 0.79 CA2 (0.37) MAOAMAOBANPEPHPGDALDH1A1
SCHEMBL27414742 0.78 MAOA (0.35) MAOAMAOBANPEPHPGDALDH1A1
SCHEMBL1783171 0.77 MAOB (0.43) MAOAMAOBANPEPHPGDNISCH
SCHEMBL27279376 0.75 TSHR (0.39) MAOAMAOBALDH1A1DAOTSHR
SCHEMBL11286717 0.75 CES2 (0.43) MAOAMAOB
Alcohol SCHEMBL28058739 0.73 KMT2A (0.39) MAOBHPGDALDH1A1
SCHEMBL7664111 0.73 MAOB (0.43) MAOAMAOBANPEPHPGDNISCH
SCHEMBL2424577 0.73 TSHR (0.48) MAOAMAOBANPEPNISCHTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108299364-B A kind of synthetic method of 2- methylol chromanone 常州大学 2019-07-09 CN claimed
CN-108299364-A A kind of synthetic method of 2- methylols chromanone 常州大学 2018-07-20 CN claimed
CN-108409699-B A kind of 2- alkyl replaces the synthetic method of chroman ketone compound 常州大学 2019-10-11 CN disclosed
CN-108299364-B A kind of synthetic method of 2- methylol chromanone 常州大学 2019-07-09 CN disclosed
CN-108299364-B A kind of synthetic method of 2- methylol chromanone 常州大学 2019-07-09 CN disclosed
CN-108299364-B A kind of synthetic method of 2- methylol chromanone 常州大学 2019-07-09 CN disclosed
CN-108299364-A A kind of synthetic method of 2- methylols chromanone 常州大学 2018-07-20 CN disclosed
CN-108299364-A A kind of synthetic method of 2- methylols chromanone 常州大学 2018-07-20 CN disclosed