Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230416 | 0.85 | PTGS2 (0.56) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL28451943 | 0.83 | PTGS2 (0.57) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL28459879 | 0.83 | PTGS2 (0.57) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL31469512 | 0.83 | PTGS2 (0.52) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL28229563 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL28579357 | 0.81 | KEAP1 (0.44) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL29710494 | 0.81 | KEAP1 (0.44) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL29009134 | 0.81 | PTGS2 (0.42) | PTGS2PTGS1CA1CA2GAA | |
| SCHEMBL29009126 | 0.81 | NR1H4 (0.50) | PTGS2PTGS1CA1CA2NPC1 | |
| SCHEMBL28229558 | 0.81 | PTGS2 (0.59) | PTGS2PTGS1CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218917-B | Preparation method of (1-aminovinyl) phosphine oxide derivative | 广西大学 | 2020-08-18 | — | — | CN | claimed |
| CN-108218917-A | A kind of (1- amine vinyls) phosphine oxygen derivative and preparation method thereof | 广西大学 | 2018-06-29 | — | — | CN | claimed |
| CN-108218917-B | Preparation method of (1-aminovinyl) phosphine oxide derivative | 广西大学 | 2020-08-18 | — | — | CN | disclosed |
| CN-108218917-A | A kind of (1- amine vinyls) phosphine oxygen derivative and preparation method thereof | 广西大学 | 2018-06-29 | — | — | CN | disclosed |