SCHEMBL28229563

SCHEMBL28229563

CS(=O)(=O)n1cc(-c2ccccc2)nn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 7/20 0.55
PTGS1 P23219 4/20 0.55
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CA5A P35218 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
CYP19A1 P11511 3/20 0.45
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
BCHE P06276 1/20 0.42
OGT O15294 1/20 0.40
SRC P12931 1/20 0.39
MEN1 O00255 1/20 0.39
CASP3 P42574 1/20 0.39
KMT2A Q03164 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31469512 0.97 PTGS2 (0.52) PTGS2PTGS1CA12CA1CA2
SCHEMBL28230416 0.84 PTGS2 (0.56) PTGS2PTGS1CA12CA1CA2
SCHEMBL28229596 0.83 PTGS2 (0.41) PTGS2PTGS1CA12CA1CA2
SCHEMBL28459879 0.83 PTGS2 (0.57) PTGS2PTGS1CA12CA1CA2
SCHEMBL28451943 0.83 PTGS2 (0.57) PTGS2PTGS1CA1CA2CA5A
SCHEMBL29710493 0.82 CA2 (0.55) CA12CA1CA2CA9CA5A
SCHEMBL28559130 0.82 CA2 (0.55) CA12CA1CA2CA9CA5A
SCHEMBL28392918 0.81 PTGS2 (0.48) PTGS2PTGS1CA12CA1CA2
SCHEMBL31469506 0.81 KEAP1 (0.45) PTGS2PTGS1CA12CA1CA2
SCHEMBL29710494 0.81 KEAP1 (0.44) PTGS2PTGS1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108218917-B Preparation method of (1-aminovinyl) phosphine oxide derivative 广西大学 2020-08-18 CN claimed
CN-119490463-A Beta-triazole derivative and synthetic method and application thereof 华东师范大学 2025-02-21 CN disclosed
CN-116178286-B N (N)2Alkyl substituted triazole derivative and synthetic method and application thereof 华东师范大学 2024-12-03 CN disclosed
CN-116178286-A High-selectivity N 2 Alkyl substituted triazole derivative and synthetic method and application thereof 华东师范大学 2023-05-30 CN disclosed
CN-111170955-B Green preparation method of 2H-1,2,3-triazole compound 河南师范大学 2023-04-07 CN disclosed
CN-112125891-B N2Selective tetrahydrofuran/tetrahydrothiophene substituted triazole derivative and synthesis method and application thereof 华东师范大学 2022-06-07 CN disclosed
CN-112125891-A N2Selective tetrahydrofuran/tetrahydrothiophene substituted triazole derivative and synthesis method and application thereof 华东师范大学 2020-12-25 CN disclosed
CN-108218917-B Preparation method of (1-aminovinyl) phosphine oxide derivative 广西大学 2020-08-18 CN disclosed
CN-111170955-A Green preparation method of 2H-1,2, 3-triazole compound 河南师范大学 2020-05-19 CN disclosed
CN-108218917-A A kind of (1- amine vinyls) phosphine oxygen derivative and preparation method thereof 广西大学 2018-06-29 CN disclosed