Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26343023 | 0.90 | FFAR1 (0.57) | FFAR1TAAR1POLBTP53MMP12 | |
| SCHEMBL315728 | 0.87 | SLC6A3 (0.63) | FFAR1SLC6A3HDAC3MAPK1ADRA1A | |
| SCHEMBL28229643 | 0.83 | MMP12 (0.41) | FFAR1SLC6A3HDAC3MAPK1ADRA1A | |
| SCHEMBL1205707 | 0.82 | MAPT (0.62) | FFAR1SLC6A3HDAC3MAPK1ADRA1A | |
| SCHEMBL7239123 | 0.81 | HDAC1 (0.70) | FFAR1SLC6A3HDAC3MAPK1ADRA1A | |
| SCHEMBL1206928 | 0.81 | MAPT (0.66) | FFAR1SLC6A3HDAC3MAPK1ADRA1A | |
| SCHEMBL2090292 | 0.80 | TAAR1 (0.56) | FFAR1SLC6A3TAAR1NAAADRD2 | |
| SCHEMBL27814786 | 0.80 | FFAR1 (0.49) | FFAR1MAPK1POLB | |
| SCHEMBL27802263 | 0.80 | LMNA (0.56) | FFAR1SLC6A3HDAC3MAPK1ADRA1A | |
| SCHEMBL334758 | 0.80 | FFAR1 (0.68) | FFAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036014-A | A kind of compound and its preparation and application with AXL inhibitory activity | 中国科学院上海药物研究所 | 2019-07-19 | — | — | CN | disclosed |
| CN-108250200-A | A kind of compound and its preparation and application with Axl inhibitory activity | 中国科学院上海药物研究所 | 2018-07-06 | — | — | CN | disclosed |