Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18764728 | 0.87 | TDP1 (0.45) | MEN1GAAKMT2ATDP1ACE | |
| SCHEMBL9980668 | 0.86 | CAPN1 (0.54) | MEN1GAAKMT2ATDP1ACE | |
| SCHEMBL16765446 | 0.85 | MEN1 (0.46) | MEN1GAAKMT2ATDP1ACE | |
| SCHEMBL16790408 | 0.85 | MEN1 (0.46) | MEN1GAAKMT2ATDP1ACE | |
| SCHEMBL31488854 | 0.82 | MEN1 (0.44) | MEN1GAAKMT2ATDP1ACE | |
| SCHEMBL25968310 | 0.82 | KMT2A (0.54) | MEN1GAAKMT2ATDP1ACE | |
| SCHEMBL9980629 | 0.82 | KMT2A (0.54) | MEN1GAAKMT2ATDP1ACE | |
| SCHEMBL47290 | 0.81 | TGFBR1 (0.52) | MEN1GAAKMT2AACETGFBR1 | |
| SCHEMBL47301 | 0.81 | TGFBR1 (0.52) | MEN1GAAKMT2AACETGFBR1 | |
| SCHEMBL315980 | 0.81 | TGFBR1 (0.52) | MEN1GAAKMT2AACETGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290878-A | NOVEL FERROPORTIN INHIBITORS | 威佛（国际）股份公司 | 2018-07-17 | — | — | CN | disclosed |