Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28231754 | 0.87 | ACHE (0.50) | ACHERAB9ANPC1SMN1; SMN2EPHX1 | |
| SCHEMBL8909168 | 0.80 | ACHE (0.53) | ACHERAB9ANPC1SMN1; SMN2EPHX1 | |
| SCHEMBL856208 | 0.78 | ACHE (0.50) | ACHERAB9ANPC1SMN1; SMN2EPHX1 | |
| SCHEMBL3956624 | 0.77 | ACHE (0.53) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL3947780 | 0.74 | ACHE (0.59) | ACHEEPHX1 | |
| SCHEMBL7048610 | 0.74 | ACHE (0.50) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL28231760 | 0.73 | ACHE (0.62) | ACHEEPHX1 | |
| SCHEMBL1534985 | 0.73 | ACHE (0.53) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL8800666 | 0.73 | ACHE (0.51) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL3395703 | 0.73 | RAB9A (0.49) | ACHERAB9ANPC1SMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290878-A | NOVEL FERROPORTIN INHIBITORS | 威佛（国际）股份公司 | 2018-07-17 | — | — | CN | disclosed |