Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909168 | 0.79 | ACHE (0.53) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL3956624 | 0.79 | ACHE (0.53) | ACHEEPHX1ALDH1A1ATM | |
| SCHEMBL3627549 | 0.77 | ACHE (0.58) | ACHEEPHX1ALDH1A1ATM | |
| SCHEMBL28231754 | 0.77 | ACHE (0.50) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL856208 | 0.77 | ACHE (0.50) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL6970951 | 0.76 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL8800666 | 0.75 | ACHE (0.51) | ACHEEPHX1ALDH1A1ATM | |
| SCHEMBL1534985 | 0.75 | ACHE (0.53) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL4764643 | 0.74 | ACHE (0.51) | ACHEEPHX1 | |
| SCHEMBL28230804 | 0.74 | ACHE (0.47) | ACHEEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | disclosed |
| EP-1259499-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060808-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |