Hexamethylbenzene

Hexamethylbenzene

SCHEMBL28232121

CC(C)(N=C=O)c1ccccc1C(C)(C)N=C=O.Cc1c(C)c(C)c(C)c(C)c1C

nearest known ligand 0.38

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145276 0.94 ALDH1A1 (0.34) CYP3A4ALDH1A1TSHRTDP1
SCHEMBL29483754 0.94 ALDH1A1 (0.34) CYP3A4ALDH1A1TSHRTDP1
SCHEMBL6831708 0.86 GABRA1 (0.35) CYP3A4ALDH1A1TSHRTDP1
SCHEMBL11038317 0.79 CYP3A4 (0.33) CYP3A4
SCHEMBL6704455 0.79 CYP3A4 (0.47) CYP3A4ALDH1A1TDP1
SCHEMBL10897571 0.77 ALDH1A1 (0.36) CYP3A4ALDH1A1TSHRTDP1
SCHEMBL7096568 0.77 CYP3A4 (0.41) CYP3A4ALDH1A1TSHR
SCHEMBL8763203 0.77 GABRA1 (0.36) CYP3A4
SCHEMBL31485790 0.77 CYP3A4 (0.41) CYP3A4ALDH1A1TSHR
SCHEMBL5597108 0.77 CYP3A4 (0.34) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107250125-B Novel episulfide compounds and the composition for optical material comprising it 三菱瓦斯化学株式会社 2018-07-13 CN disclosed