Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31485790 | 1.00 | CYP3A4 (0.41) | CYP3A4ALDH1A1CYP2C19GABRA1GABRB2 | |
| SCHEMBL15859161 | 0.85 | HSD11B1 (0.32) | CYP3A4ALDH1A1CYP2C19HSD11B1 | |
| SCHEMBL2535314 | 0.83 | CYP3A4 (0.35) | CYP3A4ALDH1A1CYP2C19GABRA1GABRB2 | |
| SCHEMBL145276 | 0.82 | ALDH1A1 (0.34) | CYP3A4ALDH1A1GABRA1GABRB2CA2 | |
| SCHEMBL29483754 | 0.82 | ALDH1A1 (0.34) | CYP3A4ALDH1A1GABRA1GABRB2CA2 | |
| SCHEMBL3358122 | 0.82 | GABRA1 (0.38) | CYP3A4ALDH1A1CYP2C19GABRA1GABRB2 | |
| SCHEMBL4779751 | 0.78 | MIF (0.34) | — | |
| Hexamethylbenzene SCHEMBL28232121 | 0.77 | CYP3A4 (0.38) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL11171834 | 0.77 | GABRA1 (0.34) | CYP3A4GABRA1LMNATSHRGABRB1 | |
| SCHEMBL810970 | 0.76 | CYP3A4 (0.39) | CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337567-A1 | GRAFT COPOLYMERS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2003-08-27 | — | — | EP | claimed |
| WO-2002036648-A1 | GRAFT COPOLYMERS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2002-05-10 | — | — | WO | claimed |
| CN-117964892-A | Modified macromer, preparation method thereof and application thereof in polymer polyol | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-110283308-A | A kind of preparation method of the stabilizer for synthesis of polymer polyalcohol | 南京金栖化工集团有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-104788733-B | A kind of isocyanate-crosslinked soybean oil based resin/natural-fiber composite material | 福建农林大学 | 2016-10-05 | — | — | CN | disclosed |
| US-5389432-A | Nonwoven fabric of web of fibers and binder | ALLIEDSIGNAL INC. (US) | 1995-02-14 | — | — | US | disclosed |