SCHEMBL282328

SCHEMBL282328

COCOc1ccc(C=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.59
CYP2A6 P11509 2/20 0.59
SMN1; SMN2 Q16637 3/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 2/20 0.53
LMNA P02545 2/20 0.53
ALDH1A3 P47895 1/20 0.48
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
KDM4E B2RXH2 4/20 0.46
RAB9A P51151 1/20 0.45
STS P08842 1/20 0.42
FDPS P14324 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8754251 0.87 ALDH1A1 (0.56) ALDH1A1CYP2A6SMN1; SMN2MAPTHPGD
SCHEMBL14996346 0.86 ALDH1A1 (0.76) ALDH1A1CYP2A6SMN1; SMN2MAPTHPGD
SCHEMBL1524953 0.85 ALDH1A1 (0.52) ALDH1A1CYP2A6SMN1; SMN2MAPTHPGD
SCHEMBL657580 0.83 ALDH1A1 (0.46) ALDH1A1CYP2A6SMN1; SMN2MAPTHPGD
SCHEMBL4693722 0.83 RELA (0.53) MAPTPTPN1
SCHEMBL12567393 0.83 RELA (0.53) MAPTPTPN1
SCHEMBL4693719 0.83 RELA (0.53) MAPTPTPN1
Propene SCHEMBL10513668 0.82 ALDH1A1 (0.42) ALDH1A1CYP2A6SMN1; SMN2MAPTHPGD
SCHEMBL3589633 0.82 NQO1 (0.50) MAPTKDM4E
SCHEMBL246323 0.82 ALDH1A1 (0.61) ALDH1A1CYP2A6SMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027243-A1 AMPHIPHILIC COMPOUNDS FOR ATTENUATING NEUROTOXICITY OF AMYLOID-beta OLIGOMERS AND DIAGNOSTIC METHODS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2026-01-29 US disclosed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
EP-4630413-A1 FLAVANONE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS Firmenich Incorporated (US) 2025-10-15 EP disclosed
US-20250221944-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT KBLUEBIO INC (KR) 2025-07-10 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20250134146-A1 FLAVANONE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH INCORPORATED (US) 2025-05-01 US disclosed
CN-115697980-B Substituted aminothiazoles as DGKZETA inhibitors for immune activation 拜耳公司 2025-03-21 CN disclosed
US-20250090565-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YewSavin, Inc. (US) 2025-03-20 US disclosed
CN-119504685-A Benzopyran flavonoid compound, preparation method and application thereof, and pharmaceutical preparation 南开大学 2025-02-25 CN disclosed
EP-4506328-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT KBlueBio Inc (KR) 2025-02-12 EP disclosed
US-5106871-A Reduced side effects TSUMURA & CO. (JP) 1992-04-21 US disclosed
CN-1036795-A PEPTIDE DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 1989-11-01 CN disclosed
EP-0336230-A2 Cyclic peptide antagonists of Substance P and Substance K FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-10-11 EP disclosed
EP-0292576-A1 ANTI-ULCEROUS AGENT CONTAINING CHALCONE DERIVATIVE AS EFFECTIVE INGREDIENT AND NOVEL CHALCONE DERIVATIVES TSUMURA & CO. (JP) 1988-11-30 EP disclosed
EP-0057162-B1 PROCESS FOR THE PRODUCTION OF IMAGES CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4368253-A Image formation process CIBA-GEIGY CORPORATION (US) 1983-01-11 US disclosed
EP-0057162-A1 Process for the production of images CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed
US-4327088-A ANTIVIRAL AGENTS HOFFMANN-LA ROCHE INC. (US) 1982-04-27 US disclosed
EP-0021000-A2 Substituted acetophenones, their preparation and pharmaceutical compositions containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-01-07 EP disclosed
US-3987105-A PROCESS FOR METHOXYMETHYLATION OF PHENOLIC HYDROXYL GROUPS AMERICAN HOME PRODUCTS CORPORATION (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027243-A1 AMPHIPHILIC COMPOUNDS FOR ATTENUATING NEUROTOXICITY OF AMYLOID-beta OLIGOMERS AND DIAGNOSTIC METHODS APP, BACE1, PSEN1 ALDH1A1 2948/4885CYP2A6 4421/4885SMN1; SMN2 427/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ALDH1A1 3285/4885CYP2A6 670/4885SMN1; SMN2 3415/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885CYP2A6 1665/4885SMN1; SMN2 4161/4885
US-20250090565-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, TFPI, SERPINE1 ALDH1A1 2859/4885CYP2A6 1473/4885SMN1; SMN2 4155/4885
US-20250221944-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT MCL1, CRBN, BCL3 ALDH1A1 1814/4885CYP2A6 2119/4885SMN1; SMN2 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.