Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17162079 | 0.96 | APP (0.47) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28026417 | 0.93 | POLB (0.45) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28861886 | 0.93 | LMNA (0.44) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28904086 | 0.85 | MEN1 (0.59) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27982971 | 0.84 | RAB9A (0.62) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27574189 | 0.83 | NPC1 (0.48) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20874025 | 0.83 | LMNA (0.49) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28191611 | 0.82 | ALDH1A1 (0.47) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9855850 | 0.80 | TP53 (0.47) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9856033 | 0.79 | ACACB (0.43) | LMNATP53NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039356-B | For chitosan targeted delivery and that small molecule integrin antagonist is covalently attached | 弗·哈夫曼-拉罗切有限公司 | 2018-08-17 | — | — | CN | disclosed |