Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | CA1 | P00915 | 4/20 | 0.71 |
| ▸ | CDK2 | P24941 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.71 |
| ▸ | FYN | P06241 | 2/20 | 0.71 |
| ▸ | MMP9 | P14780 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.71 |
| ▸ | MMP2 | P08253 | 1/20 | 0.71 |
| ▸ | MMP8 | P22894 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | MMP12 | P39900 | 1/20 | 0.71 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.71 |
| ▸ | DBH | P09172 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrogallol SCHEMBL17768460 | 0.88 | ALDH1A1 (0.71) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL28963965 | 0.86 | ALDH1A1 (0.67) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL170157 | 0.84 | ALDH1A1 (1.00) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL3532 | 0.84 | — | — | |
| Pyrogallol SCHEMBL28963966 | 0.83 | ALDH1A1 (0.63) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL209233 | 0.83 | ALDH1A1 (0.63) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL214769 | 0.83 | ALDH1A1 (0.63) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL2063415 | 0.81 | ALDH1A1 (0.80) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL483095 | 0.81 | ALDH1A1 (0.80) | CA2ALDH1A1LMNAHPGDALOX15 | |
| Pyrogallol SCHEMBL27674772 | 0.81 | ALDH1A1 (0.80) | CA2ALDH1A1LMNAHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299256-B | A kind of 2,3,4- trihydroxy benzene sulfamide derivative and its preparation method and application | 武汉大学 | 2019-09-10 | — | — | CN | claimed |
| CN-108299256-A | A kind of 2,3,4- trihydroxy benzenes sulfamide derivative and its preparation method and application | 武汉大学 | 2018-07-20 | — | — | CN | claimed |
| CN-108299256-B | A kind of 2,3,4- trihydroxy benzene sulfamide derivative and its preparation method and application | 武汉大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108299256-B | A kind of 2,3,4- trihydroxy benzene sulfamide derivative and its preparation method and application | 武汉大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108299256-B | A kind of 2,3,4- trihydroxy benzene sulfamide derivative and its preparation method and application | 武汉大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108299256-A | A kind of 2,3,4- trihydroxy benzenes sulfamide derivative and its preparation method and application | 武汉大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-108299256-A | A kind of 2,3,4- trihydroxy benzenes sulfamide derivative and its preparation method and application | 武汉大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-108299256-A | A kind of 2,3,4- trihydroxy benzenes sulfamide derivative and its preparation method and application | 武汉大学 | 2018-07-20 | — | — | CN | disclosed |