Pyrogallol

Pyrogallol

SCHEMBL209233

CS(=O)(=O)O.CS(=O)(=O)O.CS(=O)(=O)O.Oc1cccc(O)c1O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of Pyrogallol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR known ✓ P00533 1/20 0.63
MAOB known ✓ P27338 1/20 0.39
ALDH1A1 P00352 3/20 0.63
LMNA P02545 3/20 0.63
HPGD P15428 3/20 0.63
ALOX15 P16050 3/20 0.63
HSD17B10 Q99714 3/20 0.63
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63
CDK2 P24941 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
ADAMTS4 O75173 1/20 0.63
FYN P06241 1/20 0.63
MMP2 P08253 1/20 0.63
MMP9 P14780 1/20 0.63
MMP8 P22894 1/20 0.63
CA6 P23280 1/20 0.63
MMP12 P39900 1/20 0.63
RECQL P46063 1/20 0.63
ADAMTS5 Q9UNA0 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrogallol SCHEMBL214769 1.00 ALDH1A1 (0.63) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL4255147 0.91 CA1 (0.52) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL17768460 0.89 ALDH1A1 (0.71) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL28963965 0.86 ALDH1A1 (0.67) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL27897384 0.86 TRPA1 (0.74) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL1056082 0.85 ALDH1A1 (0.57) ALDH1A1LMNAHPGDALOX15HSD17B10
Catechol SCHEMBL11778548 0.83 SMN1; SMN2 (0.59) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL28234833 0.83 CA2 (0.71) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL16714223 0.80 ALDH1A1 (0.57) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL704091 0.80 ALDH1A1 (0.57) ALDH1A1LMNAHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994022-A BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID JSR CORPORATION (JP) 1999-11-30 US claimed
US-20240199854-A1 COMPOSITION, CURED FILM, STRUCTURAL BODY, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD OF CURED FILM FUJIFLIM CORPORATION (JP) 2024-06-20 US disclosed
WO-2024070845-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN SHEET, CURED PRODUCT, CURED PRODUCT PRODUCTION METHOD, SEMICONDUCTOR DEVICE, DISPLAY DEVICE, AND RESIN PRODUCTION METHOD 東レ株式会社 2024-04-04 WO disclosed
WO-2023248887-A1 POSITIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, POSITIVE TYPE PHOTOSENSITIVE RESIN SHEET, CURED PRODUCT, CURED PRODUCT MANUFACTURING METHOD, SEMICONDUCTOR DEVICE, AND DISPLAY DEVICE 東レ株式会社 2023-12-28 WO disclosed
WO-2023032746-A1 COMPOSITION, CURED FILM, STRUCTURE, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND METHOD FOR PRODUCING CURED FILM 富士フイルム株式会社 2023-03-09 WO disclosed
EP-3203320-B9 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELEMENT PROVIDED WITH CURED FILM, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE TORAY INDUSTRIES (JP) 2020-05-06 EP disclosed
EP-3203320-B1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELEMENT PROVIDED WITH CURED FILM, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE TORAY INDUSTRIES (JP) 2019-10-23 EP disclosed
US-10409163-B2 Photosensitive resin composition, cured film, element provided with cured film, and method for manufacturing semiconductor device TORAY INDUSTRIES, INC. (JP) 2019-09-10 US disclosed
EP-2799928-B1 PHOTOSENSITIVE RESIN COMPOSITION AND PROCESS FOR PRODUCING SEMICONDUCTOR ELEMENT TORAY INDUSTRIES (JP) 2019-05-22 EP disclosed
US-20170285477-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELEMENT PROVIDED WITH CURED FILM, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE TORAY INDUSTRIES, INC. (JP) 2017-10-05 US disclosed
EP-0843220-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-20 EP disclosed
EP-0838727-A1 Radiation sensitive composition Clariant International Ltd. (CH) 1998-04-29 EP disclosed
EP-0831369-A2 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1998-03-25 EP disclosed
EP-0827970-A2 New acid-labile group protected hydroxystyrene polymers or copolymers thereof and their application to radiation sensitive materials Clariant AG (CH) 1998-03-11 EP disclosed
US-5716756-A POSITIVE OR NEGATIVE WORKING MIXTURES HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-10 US disclosed
EP-0803775-A1 Positive working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1997-10-29 EP disclosed
EP-0795786-A2 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-17 EP disclosed
EP-0794457-A2 Positive working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-10 EP disclosed
EP-0607899-A2 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-07-27 EP disclosed
EP-0588544-A2 Fine pattern forming material and pattern formation process WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1994-03-23 EP disclosed