Toluene

Toluene

SCHEMBL28236261

Cc1ccccc1.Nc1ccc(C(F)(F)F)cc1N

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
L3MBTL1 Q9Y468 4/20 0.51
MAPT P10636 4/20 0.51
KDM4E B2RXH2 3/20 0.51
GAA P10253 2/20 0.51
MEN1 O00255 1/20 0.51
GFER P55789 1/20 0.51
KMT2A Q03164 1/20 0.51
PKM P14618 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CFTR P13569 1/20 0.42
TSHR P16473 3/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161784 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL29505675 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1MAPTKDM4EGAA
Ammonia Solution, Strong SCHEMBL21693609 0.82 ALDH1A1 (0.53) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL378246 0.76 ALDH1A1 (0.52) ALDH1A1L3MBTL1MAPTKDM4EGAA
Trifluoromethylbenzene SCHEMBL4239834 0.75 TSHR (0.74) ALDH1A1TSHRMAPK1RAB9ANFE2L2
SCHEMBL12979851 0.75 ALDH1A1 (0.43) ALDH1A1L3MBTL1MAPTKDM4EGAA
Hydrochloric Acid SCHEMBL6062984 0.74 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL330442 0.74 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL4158192 0.73 CYP3A4 (0.48) ALDH1A1L3MBTL1MAPTKDM4EPKM
SCHEMBL11689624 0.72 ALDH1A1 (0.48) ALDH1A1L3MBTL1MAPTKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108435224-A The preparation of hafnium C catalyst and its application in benzimidazole parallel projects 江西科技师范大学 2018-08-24 CN disclosed