SCHEMBL28237336

SCHEMBL28237336

CC=CC(=O)OCCOc1ccc(C(CC)c2ccc(OCCOC(=O)C=CC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FFAR1 O14842 1/20 0.39
FAAH O00519 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 2/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28269392 0.93 TDP1 (0.43) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL28581958 0.86 THRB (0.44) THRBTDP1MEN1KMT2ASMN1; SMN2
SCHEMBL193848 0.84 THRB (0.66) THRBALDH1A1TSHRTDP1MEN1
SCHEMBL10336222 0.83 POLB (0.44) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL27544181 0.82 ESR1 (0.46) THRBALDH1A1TSHRMEN1KMT2A
SCHEMBL11722220 0.82 THRB (0.66) THRBALDH1A1TSHRTDP1MEN1
SCHEMBL11722239 0.82 THRB (0.66) THRBALDH1A1TSHRTDP1MEN1
SCHEMBL21496022 0.81 L3MBTL1 (0.51) THRBMEN1KMT2ASMN1; SMN2L3MBTL1
SCHEMBL3886442 0.80 THRB (0.59) THRBALDH1A1TSHRTDP1MEN1
SCHEMBL20512329 0.80 ALDH1A1 (0.54) THRBALDH1A1MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110105736-A Hot curing resin composition, tubular molding compound and its formed products DIC株式会社 2019-08-09 CN disclosed
CN-109690363-A Hard coat laminate, molded body, and method for producing same 株式会社大赛璐 2019-04-26 CN disclosed
CN-109562025-A Powder liquid type basal seat area built-in material 株式会社德山齿科 2019-04-02 CN disclosed
CN-106459555-B Composition for manufacturing an ophthalmic lens comprising a UV absorber and an anti-yellowing additive 依视路国际公司 2019-03-22 CN disclosed
CN-108474968-A The manufacturing method and eyeglass of eyeglass 豪雅镜片泰国有限公司 2018-08-31 CN disclosed
CN-108474967-A METHOD FOR MANUFACTURING SPECTACLE LENS 豪雅镜片泰国有限公司 2018-08-31 CN disclosed
CN-108359388-A Solidification compound 电化株式会社 2018-08-03 CN disclosed