Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18448734 | 0.82 | MAPK1 (0.48) | HPGDNPSR1HIF1AALDH1A1KMT2A | |
| SCHEMBL28238899 | 0.73 | FYN (0.51) | HPGDNPSR1HIF1AALDH1A1KMT2A | |
| SCHEMBL22270578 | 0.73 | ALDH1A1 (0.47) | HPGDALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL22270647 | 0.72 | CSF1R (0.41) | HIF1AALDH1A1HTTKDM4EMAPK1 | |
| SCHEMBL19091942 | 0.72 | FFAR1 (0.63) | HIF1AKMT2AHTTMEN1CYP1A2 | |
| N-Benzylaniline SCHEMBL7330342 | 0.70 | HTT (0.64) | ALDH1A1KMT2AHTTKDM4EMEN1 | |
| SCHEMBL24124718 | 0.69 | HTT (0.62) | HIF1AKMT2AHTTMEN1CYP1A2 | |
| SCHEMBL18448955 | 0.69 | HIF1A (0.47) | HIF1AKMT2AHTTKDM4EMEN1 | |
| SCHEMBL2785512 | 0.68 | ALDH1A1 (0.50) | HPGDNPSR1ALDH1A1KMT2AHTT | |
| SCHEMBL22620565 | 0.68 | FFAR1 (0.54) | HIF1AKMT2AHTTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |