SCHEMBL28239556

SCHEMBL28239556

CCc1ncccc1C.F[B-](F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
CYP2A6 P11509 1/20 0.39
EGLN1 Q9GZT9 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C19 P33261 1/20 0.36
DAO P14920 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91425 0.92
Ammonia Solution, Strong SCHEMBL28056697 0.90 NOS3 (0.46) NOS3NOS1NOS2CYP2A6EGLN1
SCHEMBL27969333 0.90 NOS3 (0.46) NOS3NOS1NOS2CYP2A6EGLN1
Hydrochloric Acid SCHEMBL14245230 0.90 NOS3 (0.46) NOS3NOS1NOS2CYP2A6EGLN1
Fluoride SCHEMBL27864222 0.90 NOS3 (0.46) NOS3NOS1NOS2CYP2A6EGLN1
Bromide SCHEMBL28273371 0.90 NOS3 (0.46) NOS3NOS1NOS2CYP2A6EGLN1
SCHEMBL28234214 0.86 NOS3 (0.41) NOS3NOS1NOS2CYP2A6EGLN1
SCHEMBL29095301 0.85 NOS2 (0.39) NOS3NOS1NOS2CYP2A6CYP1A2
Pyridine SCHEMBL28305006 0.82 CYP2A6 (0.42) NOS3NOS1NOS2CYP2A6EGLN1
SCHEMBL28129202 0.82 L3MBTL1 (0.39) NOS3NOS1NOS2CYP2A6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108663421-A A kind of preparation of nano TiC/graphene composite paste electrode sensor 济南大学 2018-10-16 CN disclosed