SCHEMBL29095301

SCHEMBL29095301

CCCc1ncccc1C.F[B-](F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
CYP2A6 P11509 1/20 0.37
SSTR4 P31391 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GRM5 P41594 1/20 0.36
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
PDE10A Q9Y233 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
DAO P14920 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10245894 0.92 NOS2 (0.45) NOS2NOS3NOS1CYP2A6SSTR4
SCHEMBL28129202 0.89 L3MBTL1 (0.39) NOS2NOS3NOS1CYP2A6SSTR4
SCHEMBL28239556 0.85 NOS3 (0.42) NOS2NOS3NOS1CYP2A6ALDH1A1
SCHEMBL8582607 0.81 L3MBTL1 (0.43) NOS2NOS3NOS1CYP2A6SSTR4
Ammonia Solution, Strong SCHEMBL28841614 0.79 L3MBTL1 (0.42) NOS2NOS3NOS1CYP2A6SSTR4
SCHEMBL15856910 0.79 L3MBTL1 (0.50) NOS2NOS3NOS1CYP2A6SSTR4
Bromide SCHEMBL28285568 0.79 L3MBTL1 (0.42) NOS2NOS3NOS1CYP2A6SSTR4
Trifluoromethanesulfonic Acid SCHEMBL30399066 0.79 SSTR4 (0.39) SSTR4ALDH1A1SMN1; SMN2MAPTCYP2C19
SCHEMBL28119974 0.79 L3MBTL1 (0.39) NOS2NOS3NOS1CYP2A6SSTR4
SCHEMBL6839265 0.78 TDP1 (0.49) NOS2NOS3NOS1CYP2A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122380-B Method for removing glycidyl ester by utilizing ionic liquid 丰益(上海)生物技术研发中心有限公司 2023-09-22 CN disclosed