Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 9/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257552 | 0.81 | ALDH1A1 (0.62) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL6968655 | 0.81 | ALDH1A1 (0.62) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL6966089 | 0.80 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL13062867 | 0.78 | PNMT (0.44) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL27897828 | 0.78 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL16115726 | 0.77 | GAA (0.54) | PNMTADRA2AADRA2BADRA2CSIRT2 | |
| SCHEMBL29697818 | 0.77 | GAA (0.54) | PNMTADRA2AADRA2BADRA2CSIRT2 | |
| SCHEMBL27470339 | 0.77 | PNMT (0.64) | PNMTADRA2AADRA2BADRA2CSIRT2 | |
| SCHEMBL10293160 | 0.77 | GAA (0.54) | PNMTADRA2AADRA2BADRA2CSIRT2 | |
| SCHEMBL28243488 | 0.77 | PNMT (0.51) | PNMTADRA2AADRA2BADRA2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440496-B | A method of preparing 2- aminoindole derivatives | 苏州大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108440496-A | A method of preparing 2- aminoindole derivatives | 苏州大学 | 2018-08-24 | — | — | CN | disclosed |