Carbazole

Carbazole

SCHEMBL28239888

N#Cc1ccccc1.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
GPR3 P46089 2/20 0.61
HSD17B10 Q99714 2/20 0.61
TSHR P16473 1/20 0.61
GABRP O00591 3/20 0.53
GABRD O14764 3/20 0.53
GABRA1 P14867 3/20 0.53
GABRB1 P18505 3/20 0.53
GABRG2 P18507 3/20 0.53
GABRB3 P28472 3/20 0.53
GABRA5 P31644 3/20 0.53
GABRA3 P34903 3/20 0.53
GABRA2 P47869 3/20 0.53
GABRB2 P47870 3/20 0.53
GABRA4 P48169 3/20 0.53
GABRE P78334 3/20 0.53
GABRA6 Q16445 3/20 0.53
GABRG1 Q8N1C3 3/20 0.53
GABRG3 Q99928 3/20 0.53
GABRQ Q9UN88 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbazole SCHEMBL28598127 1.00 ALDH1A1 (0.61) ALDH1A1GPR3HSD17B10TSHRGABRP
Carbazole SCHEMBL28870338 1.00 ALDH1A1 (0.61) ALDH1A1GPR3HSD17B10TSHRGABRP
Carbazole SCHEMBL28387749 0.88 TDO2 (0.56) ALDH1A1GPR3HSD17B10TSHRGABRP
Carbazole SCHEMBL27801512 0.83 ALDH1A1 (0.88) ALDH1A1GPR3HSD17B10GABRPGABRD
Diphenylacetylene SCHEMBL6544119 0.82 ALDH1A1 (0.67) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL30414171 0.82 KIF11 (0.58) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL31273378 0.82 CHUK (0.63) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL30480932 0.82 CHUK (0.63) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL1247669 0.82 CHUK (0.63) ALDH1A1GPR3HSD17B10GABRPGABRD
SCHEMBL6009650 0.82 KIF11 (0.58) ALDH1A1GPR3HSD17B10GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121441-B Compound and application thereof 北京鼎材科技有限公司 2024-07-16 CN disclosed
CN-117337066-A Organic light emitting device, display panel and display apparatus 京东方科技集团股份有限公司 2024-01-02 CN disclosed
CN-114685354-A Organic compound, application thereof and organic electroluminescent device comprising organic compound 北京鼎材科技有限公司 2022-07-01 CN disclosed
CN-113527180-A OLED material and application thereof 北京鼎材科技有限公司 2021-10-22 CN disclosed
CN-113121441-A Compound and application thereof 北京鼎材科技有限公司 2021-07-16 CN disclosed
CN-108503628-A A kind of organic electroluminescent compounds 上海和辉光电有限公司 2018-09-07 CN disclosed