Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 4/20 | 0.43 |
| ▸ | FABP4 | P15090 | 4/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821880 | 0.99 | FABP3 (0.45) | FABP3FABP4FABP5CYP2C9CYP3A4 | |
| SCHEMBL2825677 | 0.99 | FABP3 (0.45) | FABP3FABP4FABP5CYP2C9CYP3A4 | |
| SCHEMBL2821184 | 0.92 | SMN1; SMN2 (0.37) | FABP3FABP4FABP5CYP2C9CYP3A4 | |
| SCHEMBL2826514 | 0.92 | TACR1 (0.42) | GAAMAPTNPSR1SMN1; SMN2TACR1 | |
| SCHEMBL2822062 | 0.91 | KDM4E (0.38) | FABP3FABP4FABP5CYP2C9CYP3A4 | |
| SCHEMBL2826068 | 0.91 | NPSR1 (0.43) | GAAMAPTNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL2825467 | 0.91 | KDM4E (0.38) | FABP3FABP4FABP5CYP2C9CYP3A4 | |
| SCHEMBL2829017 | 0.88 | PTGS2 (0.43) | NR1H2 | |
| SCHEMBL2823196 | 0.88 | GAA (0.40) | FABP3FABP4FABP5CYP2C9CYP3A4 | |
| SCHEMBL2821527 | 0.87 | PTGS2 (0.45) | FABP3FABP4FABP5CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809605-B1 | QUINOLINES AS ALLOSTERIC ENHANCERS OF THE GABA-B RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | claimed |