SCHEMBL28242515

SCHEMBL28242515

Nc1nnc(Cc2ccccc2)nn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HTR6 P50406 1/20 0.41
HRH4 Q9H3N8 1/20 0.41
LTB4R Q15722 1/20 0.41
AOC3 Q16853 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
MPO P05164 1/20 0.39
ADORA2A P29274 1/20 0.38
ADORA2B P29275 1/20 0.38
ADORA1 P30542 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15323022 0.88 CALM1 (0.61) CALM1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL15323583 0.77 CALM1 (0.48) CALM1ALDH1A1TAAR1HRH3LTA4H
SCHEMBL3416553 0.77 HTR6 (0.57) CALM1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29076175 0.76 TDP1 (0.56) CALM1ALDH1A1AOC3TAAR1HRH3
SCHEMBL21372063 0.74 CALM1 (0.50) CALM1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL30281263 0.74 ALDH1A1 (0.57) ALDH1A1CYP2D6HTR6TAAR1LTA4H
SCHEMBL28815533 0.72 MPO (0.54) CALM1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL2614741 0.72 CALM1 (0.61) CALM1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL28267391 0.71 NPC1 (0.53) CALM1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL13437610 0.71 AOC3 (0.48) CALM1ALDH1A1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108542832-A A kind of antibacterial liquid tooth paste 佛山皖阳生物科技有限公司 2018-09-18 CN claimed
CN-108542832-A A kind of antibacterial liquid tooth paste 佛山皖阳生物科技有限公司 2018-09-18 CN disclosed