Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 4/20 | 0.32 |
| ▸ | MMP9 | P14780 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32676394 | 0.82 | CA1 (0.37) | ALDH1A1MAPTTGFBR1CA2MAPK1 | |
| Trifluoroacetic Acid SCHEMBL5130366 | 0.78 | CA1 (0.34) | ALDH1A1MAPTCA2MMP2MMP9 | |
| SCHEMBL10076157 | 0.77 | ITGB3 (0.39) | ALDH1A1MAPTTGFBR1MMP2MMP9 | |
| SCHEMBL24108521 | 0.77 | ITGB3 (0.39) | ALDH1A1MAPTTGFBR1MMP2MMP9 | |
| SCHEMBL14215470 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TGFBR1MMP2MMP9CYP2C19 | |
| SCHEMBL16697543 | 0.71 | CA12 (0.55) | CA2CTSSCTSKCA1 | |
| SCHEMBL25587867 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MMP2THRBALOX15SMN1; SMN2 | |
| SCHEMBL25587869 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MMP2THRBALOX15SMN1; SMN2 | |
| SCHEMBL25587870 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MMP2THRBALOX15SMN1; SMN2 | |
| SCHEMBL17245269 | 0.70 | CA2 (0.37) | ALDH1A1MAPTCA2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602805-A | Isoindoline, azaisoindoline, indenone and the dihydro azepine indone inhibitor of MNK1 and MNK2 | 效应治疗股份有限公司 | 2018-09-28 | — | — | CN | disclosed |