Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143781 | 0.93 | TSHR (0.50) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL7921709 | 0.93 | TSHR (0.50) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL1143779 | 0.93 | TSHR (0.50) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL6663448 | 0.83 | CTSD (0.56) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL6663445 | 0.83 | CTSD (0.56) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL7933746 | 0.79 | RAB9A (0.66) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL14691237 | 0.79 | SMN1; SMN2 (0.59) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL2649166 | 0.79 | SMN1; SMN2 (0.59) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL6661082 | 0.79 | RAB9A (0.66) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL6661088 | 0.79 | RAB9A (0.66) | PDE4APDE4BPDE4CPDE4DNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484514-A | The preparation method of platelet derived growth factor receptor inhibitor AG1296 | 广西师范大学 | 2018-09-04 | — | — | CN | claimed |
| CN-108484514-A | The preparation method of platelet derived growth factor receptor inhibitor AG1296 | 广西师范大学 | 2018-09-04 | — | — | CN | disclosed |