Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL950218 | 0.83 | LMNA (0.73) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL353141 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL105459 | 0.81 | SMN1; SMN2 (0.70) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL29412848 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL29799007 | 0.81 | SMN1; SMN2 (0.70) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL17180592 | 0.81 | LMNA (0.70) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL30792459 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| Hydrochloric Acid SCHEMBL2683707 | 0.79 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL5250407 | 0.79 | SMN1; SMN2 (0.96) | LMNASMN1; SMN2POLBL3MBTL1EGFR | |
| SCHEMBL38770 | 0.79 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2POLBL3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602799-A | A kind of kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2018-09-28 | — | — | CN | disclosed |