SCHEMBL38770

SCHEMBL38770

NC(=O)c1cccnc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.68
LMNA P02545 1/20 0.68
PARP1 P09874 1/20 0.56
RAB9A P51151 2/20 0.54
POLB P06746 1/20 0.50
NPC1 O15118 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
EGFR P00533 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 1/20 0.47
NAPRT Q6XQN6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30680438 1.00 SMN1; SMN2 (0.68) SMN1; SMN2LMNAPARP1RAB9APOLB
Hydrochloric Acid SCHEMBL5008498 0.98 SMN1; SMN2 (0.66) SMN1; SMN2LMNAPARP1RAB9APOLB
Hydrochloric Acid SCHEMBL28905020 0.98 SMN1; SMN2 (0.66) SMN1; SMN2LMNAPARP1RAB9APOLB
Biphenyl SCHEMBL21043711 0.91 SMN1; SMN2 (0.62) SMN1; SMN2LMNAPARP1RAB9APOLB
SCHEMBL28755796 0.83 SMN1; SMN2 (0.49) SMN1; SMN2LMNAPARP1RAB9APOLB
SCHEMBL950218 0.83 LMNA (0.73) SMN1; SMN2LMNAPOLBNPC1L3MBTL1
SCHEMBL30475735 0.81 SMN1; SMN2 (0.59) SMN1; SMN2LMNAPARP1POLBNPC1
SCHEMBL17180592 0.81 LMNA (0.70) SMN1; SMN2LMNAPOLBNPC1L3MBTL1
SCHEMBL580815 0.81 LMNA (0.59) SMN1; SMN2LMNAPARP1RAB9APOLB
SCHEMBL105459 0.81 SMN1; SMN2 (0.70) SMN1; SMN2LMNAPOLBNPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094660-A Composition in the form of an oil-in-water emulsion 2026-05-26 CN claimed
EP-4687829-A1 COMPOSITION FOR CARING FOR KERATIN MATERIALS L'OREAL (FR) 2026-02-11 EP claimed
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2025-12-18 US claimed
US-20250161201-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2025-05-22 US claimed
WO-2025091220-A2 COMPOSITION IN THE FORM OF OIL-IN-WATER EMULSION L'OREAL (FR) 2025-05-08 WO claimed
WO-2025091239-A1 COMPOSITION IN THE FORM OF OIL-IN-WATER EMULSION L'OREAL (FR) 2025-05-08 WO claimed
EP-4543408-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME L'OREAL (FR) 2025-04-30 EP claimed
CN-119654151-A Composition for caring skin 莱雅公司 2025-03-18 CN claimed
CN-119630382-A Solubilization of thiopyridone compounds and compositions containing same 莱雅公司 2025-03-14 CN claimed
CN-119462424-A 2-Cyano-5-dimethylamino-2, 4-pentadiene amide compound and application thereof 郑州手性药物研究院有限公司 2025-02-18 CN claimed
WO-2002069916-A2 ANHYDROUS ANTIPERSPIRANT AND DEODORANT COMPOSITIONS CONTAINING A SOLID, WATER-SOLUBLE, SKIN ACTIVE AGENT THE PROCTER & GAMBLE COMPANY (US) 2002-09-12 WO claimed
US-6383476-B1 Anhydrous antiperspirant and deodorant compositions containing a solid, water-soluble, skin active agent THE PROCTER & GAMBLE COMPANY 2002-05-07 US claimed
WO-2002012442-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR NEUROGEN CORPORATION (US) 2002-02-14 WO claimed
US-6028111-A Compositions and use of benzamides and nicotinamides as anti-inflammatory agents OXIGENE, INC. (US) 2000-02-22 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0331052-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-09-06 EP claimed
EP-0315151-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-05-10 EP claimed
US-4080336-A Process for the production of 2-chloronicotinic acid amide LONZA LTD. (CH) 1978-03-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161201-A1 COSMETIC COMPOSITION CYP19A1, SHBG, HSD17B11 SMN1; SMN2 4266/4885LMNA 3019/4885PARP1 4749/4885
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME TBCB, CCNB3, CYP24A1 SMN1; SMN2 2297/4885LMNA 3917/4885PARP1 3511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.