SCHEMBL28246325

SCHEMBL28246325

CC(=O)c1c(C)c(F)c(N)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
TP53 P04637 1/20 0.33
CISD2 Q8N5K1 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
THRB P10828 1/20 0.33
TAS1R3 Q7RTX0 10/20 0.32
TAS1R1 Q7RTX1 9/20 0.32
TAS1R2 Q8TE23 9/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29092856 0.83 HSD17B10 (0.33) HSD17B10CYP1A2CYP3A4TP53CISD2
SCHEMBL9608357 0.81 TAS1R3 (0.41) HSD17B10CYP1A2CYP3A4ALDH1A1TAS1R3
SCHEMBL15180430 0.79 CES2 (0.34) HSD17B10CYP3A4TP53KDM4EALDH1A1
SCHEMBL4849062 0.77 ALDH1A1 (0.33) HSD17B10CYP3A4TP53KDM4EALDH1A1
SCHEMBL18674532 0.77 TAS1R3 (0.41) HSD17B10CYP1A2CYP3A4TAS1R3TAS1R1
SCHEMBL8374315 0.76 KMT2A (0.37) CYP1A2KDM4EALDH1A1TAS1R3TAS1R1
SCHEMBL9633943 0.74 CYP3A4 (0.39) HSD17B10CYP1A2CYP3A4HPGDTHRB
SCHEMBL6727338 0.74 TAS1R3 (0.47) HSD17B10CYP1A2CYP3A4THRBTAS1R3
SCHEMBL6668834 0.71 KMT2A (0.41) CYP1A2KDM4ETAS1R3TAS1R1TAS1R2
SCHEMBL7869943 0.71 CES2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106827642-B A kind of software flocculant extrusion formation equipment and its forming method in sewage disposal 徐州腾睿智能装备有限公司 2018-09-18 CN disclosed