Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28246584 | 0.86 | TRPM8 (0.60) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL27996874 | 0.83 | KDM4E (0.46) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL27997095 | 0.78 | GAA (0.43) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL5551093 | 0.76 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL545945 | 0.76 | SMN1; SMN2 (0.65) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL15049266 | 0.75 | TRPM8 (0.64) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28246573 | 0.75 | ALDH1A1 (0.53) | NPC1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL28245733 | 0.75 | GAA (0.46) | RAB9ANPC1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL27996876 | 0.74 | CDC7 (0.63) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL27738235 | 0.72 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | claimed |