Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 5/20 | 0.54 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049266 | 0.91 | TRPM8 (0.64) | TRPM8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28246574 | 0.86 | RAB9A (0.46) | TRPM8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28245895 | 0.85 | TRPM8 (0.58) | TRPM8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28245823 | 0.80 | CDC7 (0.57) | TRPM8MAPTMEN1KMT2ACDC7 | |
| SCHEMBL28245821 | 0.78 | CDC7 (0.57) | TRPM8MAPTMEN1KMT2ACDC7 | |
| SCHEMBL28246577 | 0.77 | MEN1 (0.61) | TRPM8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27997093 | 0.77 | CDC7 (0.74) | TRPM8MAPTMEN1KMT2ALMNA | |
| SCHEMBL27997098 | 0.77 | TRPM8 (0.78) | TRPM8MAPTMEN1KMT2ACDC7 | |
| SCHEMBL15049068 | 0.74 | TRPM8 (0.67) | TRPM8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4920930 | 0.72 | SMN1; SMN2 (0.78) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | disclosed |