Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28246804

Cc1ccc2scnc2c1.N

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
MAPK1 P28482 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HSD17B10 Q99714 1/20 0.48
RAB9A P51151 3/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
HPGD P15428 1/20 0.40
KLK7 P49862 1/20 0.40
TRPM5 Q9NZQ8 1/20 0.39
HSD11B1 P28845 1/20 0.39
HKDC1 Q2TB90 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.38
NQO2 P16083 1/20 0.38
CYP1A2 P05177 1/20 0.38
TP53 P04637 1/20 0.38
DYRK1A Q13627 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172097 0.98 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL29870586 0.98 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
Benzene SCHEMBL27598766 0.94 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
(Z)-1,2-Diphenylethene SCHEMBL27512705 0.83 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL6650934 0.82 FFAR1 (0.48) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL29870814 0.81 RAB9A (0.54) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL266440 0.81 RAB9A (0.54) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL9143839 0.79 RAB9A (0.44) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL16478922 0.78 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL27531501 0.77 CYP1A2 (0.46) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106518828-B Amides myricetin derivative, preparation method and application 贵州大学 2018-10-23 CN disclosed