SCHEMBL29870586

SCHEMBL29870586

Cc1ccc2scnc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MAPK1 P28482 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
HSD17B10 Q99714 1/20 0.50
RAB9A P51151 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.40
HPGD P15428 1/20 0.40
KLK7 P49862 1/20 0.40
TRPM5 Q9NZQ8 1/20 0.40
HSD11B1 P28845 1/20 0.40
HKDC1 Q2TB90 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NQO2 P16083 1/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 2/20 0.39
TP53 P04637 1/20 0.39
DYRK1A Q13627 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172097 1.00 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
Ammonia Solution, Strong SCHEMBL28246804 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
Benzene SCHEMBL27598766 0.96 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
(Z)-1,2-Diphenylethene SCHEMBL27512705 0.85 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL6650934 0.84 FFAR1 (0.48) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL29870814 0.83 RAB9A (0.54) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL266440 0.83 RAB9A (0.54) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL9143839 0.81 RAB9A (0.44) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL16478922 0.80 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10
SCHEMBL27531501 0.79 CYP1A2 (0.46) ALDH1A1SMN1; SMN2MAPK1NPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME CHECKMATE THERAPEUTICS INC. (KR) 2026-01-22 US disclosed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
US-20240228484-A1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-07-11 US disclosed
EP-4385641-A1 PROTECTED METAL ALLOY POWDER COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2024-06-19 EP disclosed
US-11891387-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2024-02-06 US disclosed
US-20230321067-A1 DOSING REGIMEN COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2023-10-12 US disclosed
US-20220372030-A1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2022-11-24 US disclosed
CN-115175909-A Pyrrolopyridine and imidazopyridine antiviral compounds 鲁汶天主教大学 2022-10-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228484-A1 MONOACYLGLYCEROL LIPASE MODULATORS MGLL, LPL, PNLIP ALDH1A1 252/4885SMN1; SMN2 1579/4885MAPK1 4226/4885
US-11891387-B2 Monoacylglycerol lipase modulators MGLL, LPL, PNLIP ALDH1A1 252/4885SMN1; SMN2 1579/4885MAPK1 4226/4885
US-20230321067-A1 DOSING REGIMEN COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES IKZF1, IKZF2, IKZF3 ALDH1A1 2551/4885SMN1; SMN2 755/4885MAPK1 4088/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 ALDH1A1 800/4885SMN1; SMN2 1208/4885MAPK1 419/4885
US-20220372030-A1 MONOACYLGLYCEROL LIPASE MODULATORS MGLL, LPL, PNLIP ALDH1A1 252/4885SMN1; SMN2 1579/4885MAPK1 4226/4885
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME NAMPT, NAPRT, NNT ALDH1A1 789/4885SMN1; SMN2 2571/4885MAPK1 1231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.