SCHEMBL266440

SCHEMBL266440

Cc1ccc2ncsc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.54
NPC1 O15118 7/20 0.54
ALDH1A1 P00352 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
KDM4E B2RXH2 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
HPGD P15428 1/20 0.54
KLK7 P49862 1/20 0.54
HKDC1 Q2TB90 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HSD17B10 Q99714 1/20 0.50
DYRK1A Q13627 2/20 0.49
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TGFBR1 P36897 4/20 0.41
LRRK2 Q5S007 1/20 0.41
BMPR1A P36894 1/20 0.41
SMAD2 Q15796 1/20 0.41
PRKD1 Q15139 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29870814 1.00 RAB9A (0.54) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL9143839 0.85 RAB9A (0.44) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL16573976 0.84 DYRK1A (0.60) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL11592097 0.83 RAB9A (0.46) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL29870586 0.83 ALDH1A1 (0.54) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL172097 0.83 ALDH1A1 (0.54) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
Ammonia Solution, Strong SCHEMBL28246804 0.81 ALDH1A1 (0.52) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL21944747 0.80 TDP1 (0.45) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
Benzene SCHEMBL27598766 0.79 ALDH1A1 (0.52) RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL27550527 0.79 DYRK1A (0.63) RAB9ANPC1ALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2125 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024177606-A1 QUINAZOLINONE DERIVATIVE COMPOUNDS SHOWING ANTI-CANCER ACTIVITY AND THE SYNTHESIS METHODS OF THESE COMPOUNDS BILECIK SEYH EDEBALI UNIVERSITESI (TR) 2024-08-29 WO claimed
CN-116655847-B Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara 浙江材华科技有限公司 2024-02-09 CN claimed
CN-116655847-A Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara 浙江材华科技有限公司 2023-08-29 CN claimed
CN-115433072-B Method for preparing aryl ketone by photocatalytic oxidation 浙江工业大学 2023-08-08 CN claimed
US-11667644-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2023-06-06 US claimed
CN-115112617-B Fluorescent detection method for content of heavy metal cadmium in incense 永春县产品质量检验所(福建省香产品质量检验中心、国家燃香类产品质量监督检验中心(福建)) 2023-04-21 CN claimed
CN-115504942-A Synthesis method of alkyl or acyl substituted benzothiazole derivative 汕头大学 2022-12-23 CN claimed
CN-115433072-A Method for preparing aryl ketone by photocatalytic oxidation 浙江工业大学 2022-12-06 CN claimed
CN-115112617-A Fluorescence detection method for content of burning heavy metal cadmium 永春县产品质量检验所(福建省香产品质量检验中心、国家燃香类产品质量监督检验中心(福建)) 2022-09-27 CN claimed
US-RE48841-E1 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2021-12-07 US claimed
US-5103001-A SPIRODILACTAMS SHELL OIL COMPANY (US) 1992-04-07 US claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
US-4772534-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1988-09-20 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-4654384-A DYEING PAPER, TEXTILES, LEATHER, SHADES OF RED CIBA-GEIGY CORPORATION (US) 1987-03-31 US claimed
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 US claimed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed