Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988028 | 0.72 | LMNA (0.34) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL28038419 | 0.72 | LMNA (0.34) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL8375501 | 0.72 | LMNA (0.34) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL12629758 | 0.72 | MAOA (0.37) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL28144269 | 0.72 | CYP1A2 (0.33) | LMNATDP1HDAC4HDAC7HDAC5 | |
| SCHEMBL8149969 | 0.72 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL27447709 | 0.71 | CYP11B1 (0.33) | LMNA | |
| SCHEMBL2937446 | 0.71 | POLB (0.47) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL251288 | 0.70 | DRD2 (0.41) | LMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5090888 | 0.70 | LMNA (0.33) | LMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689815-A | A kind of synthetic method of indanone compounds | 郑州德瑞医药科技有限公司 | 2018-10-23 | — | — | CN | disclosed |