Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | VNN1 | O95497 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248508 | 0.84 | VNN1 (0.50) | FFAR1VNN1KDM4EEGFRHDAC1 | |
| SCHEMBL28248630 | 0.79 | VNN1 (0.50) | FFAR1FFAR4VNN1KDM4ECHEK1 | |
| SCHEMBL4242744 | 0.79 | FFAR1 (0.66) | FFAR1FFAR4CHEK1DAPK3ROCK2 | |
| SCHEMBL5544937 | 0.78 | FFAR1 (0.58) | FFAR1FFAR4KDM4ECHEK1DAPK3 | |
| SCHEMBL6695026 | 0.77 | HDAC1 (0.55) | FFAR1FFAR4VNN1CHEK1DAPK3 | |
| SCHEMBL4352193 | 0.75 | FFAR1 (0.55) | FFAR1FFAR4CHEK1DAPK3ROCK2 | |
| SCHEMBL5226860 | 0.75 | FFAR1 (0.61) | FFAR1FFAR4KDM4ECHEK1DAPK3 | |
| SCHEMBL5180466 | 0.75 | FFAR1 (0.54) | FFAR1FFAR4CHEK1DAPK3ROCK2 | |
| SCHEMBL4351774 | 0.74 | FFAR1 (0.54) | FFAR1FFAR4CHEK1DAPK3ROCK2 | |
| SCHEMBL631859 | 0.74 | MEN1 (0.55) | FFAR1FFAR4CHEK1DAPK3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431989-B | The aminated compounds and its preparation method and application of N- halogenated aryls substitution | 云南大学 | 2018-10-16 | — | — | CN | disclosed |