Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | VNN1 | O95497 | 4/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CLPP | Q16740 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691560 | 0.86 | NOS1 (0.58) | HDAC1HDAC8HDAC6VNN1NOS1 | |
| SCHEMBL28248508 | 0.80 | VNN1 (0.50) | HDAC1HDAC8HDAC6VNN1LRRK2 | |
| SCHEMBL1680823 | 0.78 | LMNA (0.57) | HDAC1HDAC8HDAC6VNN1NOS1 | |
| SCHEMBL18223806 | 0.77 | VNN1 (0.57) | VNN1L3MBTL1MRGPRX4METKCNH2 | |
| SCHEMBL28248503 | 0.77 | FFAR1 (0.51) | HDAC1HDAC8HDAC6VNN1L3MBTL1 | |
| SCHEMBL16447573 | 0.76 | HDAC1 (0.55) | HDAC1HDAC8HDAC6VNN1NOS1 | |
| SCHEMBL10055021 | 0.75 | NPSR1 (0.55) | PPARAL3MBTL1FFAR1FFAR4ABL1 | |
| SCHEMBL6691557 | 0.73 | FFAR1 (0.54) | HDAC1HDAC6PPARAFFAR1 | |
| SCHEMBL5435247 | 0.73 | FFAR1 (0.62) | PPARAFFAR1 | |
| SCHEMBL16481496 | 0.73 | CDC7 (0.51) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | HDAC1 462/4885HDAC8 1386/4885HDAC6 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.