Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 13/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198302 | 0.81 | ALOX15 (0.50) | ALOX15BRD4CREBBP | |
| SCHEMBL2824864 | 0.75 | BRD4 (0.56) | ALOX15BRD4CREBBP | |
| SCHEMBL13313600 | 0.74 | BRD4 (0.57) | BRD4CREBBP | |
| SCHEMBL508184 | 0.70 | ALOX15 (0.98) | ALOX15 | |
| SCHEMBL508185 | 0.70 | ALOX15 (0.98) | ALOX15 | |
| SCHEMBL29468680 | 0.70 | ALOX15 (0.98) | ALOX15 | |
| SCHEMBL29462345 | 0.70 | ALOX15 (0.98) | ALOX15 | |
| SCHEMBL677636 | 0.69 | BRD4 (1.00) | BRD4CREBBP | |
| SCHEMBL9544432 | 0.69 | KDM4E (0.37) | TSHRRIPK1 | |
| SCHEMBL10414143 | 0.69 | KEAP1 (0.76) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382687-B1 | Benzofused-N-containing heterocycle derivatives | BOEHRINGER INGELHEIM ITALIA (IT) | 1995-12-27 | — | — | EP | disclosed |
| US-5106851-A | Respiratory system disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-04-21 | — | — | US | disclosed |