SCHEMBL1762833

SCHEMBL1762833

Cn1nc(C(F)F)c(C(N)=O)c1-c1ccccc1-c1cccc(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.39
POLB P06746 1/20 0.39
DCAF1 Q9Y4B6 1/20 0.38
SCN9A Q15858 4/20 0.38
GRM5 P41594 1/20 0.37
IKBKB O14920 1/20 0.37
NUDT1 P36639 1/20 0.36
MAOB P27338 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
BTK Q06187 1/20 0.35
CHRM1 P11229 2/20 0.35
ADORA1 P30542 1/20 0.35
CHRM3 P20309 1/20 0.35
IDO1 P14902 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KDM4C Q9H3R0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3325668 0.91 POLB (0.38) PTGER4POLBSCN9ACHRM3
SCHEMBL1763152 0.88 CSNK1E (0.43) POLB
SCHEMBL1762661 0.85 HSD17B10 (0.38) PTGER4POLBSCN9ACHRM1MAPT
SCHEMBL1762650 0.85 ALDH1A1 (0.39) PTGER4MAPT
SCHEMBL1762883 0.83 POLB (0.38) POLBGRM5
SCHEMBL1762849 0.83 HSD17B10 (0.44) POLBSCN9AIKBKBMAPT
SCHEMBL3232405 0.82 CSNK1D (0.41) PTGER4POLBSCN9ANUDT1
SCHEMBL1763063 0.82 MGLL (0.38) POLBCHRM3
SCHEMBL28430781 0.80 POLB (0.41) PTGER4POLBDCAF1SCN9AMAPT
SCHEMBL28248772 0.80 POLB (0.51) POLBGRM5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263327-B2 Enzymatic method for the production of microcapsules BASF SE (DE) 2012-09-11 US disclosed
US-20110124590-A1 Oil-in-Water Emulsion Comprising Solvent, Water, Surfactant and Pesticide BASF SE (DE) 2011-05-26 US disclosed
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules BASF SE 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules MGAM, ACHE, BCHE PTGER4 3258/4885POLB 565/4885DCAF1 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.