Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071553 | 0.95 | LMNA (0.31) | — | |
| Bromide SCHEMBL5150073 | 0.91 | — | — | |
| Fluoride Ion SCHEMBL5014897 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL11389158 | 0.91 | — | — | |
| SCHEMBL3310909 | 0.81 | TSHR (0.40) | — | |
| SCHEMBL3308158 | 0.81 | TSHR (0.40) | — | |
| SCHEMBL1074582 | 0.81 | — | — | |
| SCHEMBL3308004 | 0.78 | — | — | |
| SCHEMBL385569 | 0.78 | — | — | |
| SCHEMBL4231002 | 0.78 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150238948-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-08-27 | — | — | US | claimed |
| EP-2888043-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-07-01 | — | — | EP | claimed |
| WO-2014032004-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2014-02-27 | — | — | WO | claimed |
| US-20180065125-A1 | COMPOSITIONS AND METHODS FOR SEPARATING FLUIDS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-03-08 | — | — | US | disclosed |
| EP-3259073-A1 | COMPOSITIONS AND METHODS FOR SEPARATING FLUIDS | Momentive Performance Materials Inc. (US) | 2017-12-27 | — | — | EP | disclosed |
| WO-2016134231-A1 | COMPOSITIONS AND METHODS FOR SEPARATING FLUIDS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-08-25 | — | — | WO | disclosed |
| US-20150238948-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-08-27 | — | — | US | disclosed |
| EP-2888043-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014032004-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2014-02-27 | — | — | WO | disclosed |
| EP-1919853-B1 | REMOVAL OF METAL IONS FROM ONIUM HYDROXIDES AND ONIUM SALT SOLUTIONS | SACHEM INC (US) | 2010-10-27 | — | — | EP | disclosed |
| EP-1472188-B1 | PURIFICATION OF ONIUM HYDROXIDES BY ELECTRODIALYSIS | SACHEM INC (US) | 2010-10-06 | — | — | EP | disclosed |
| US-5910237-A | Process for recovering organic hydroxides from waste solutions | SACHEM, INC. (US) | 1999-06-08 | — | — | US | disclosed |
| US-5868916-A | Process for recovering organic hydroxides from waste solutions | SACHEM, INC. (US) | 1999-02-09 | — | — | US | disclosed |
| WO-1998035748-A1 | PROCESS FOR RECOVERING ORGANIC HYDROXIDES FROM WASTE SOLUTIONS | SACHEM, INC. (US) | 1998-08-20 | — | — | WO | disclosed |
| US-5753097-A | Process for purifying hydroxide compounds | SACHEM, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0834346-A2 | Process for purifying hydroxide compounds | Sachem, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0834345-A2 | Electrochemical process for purifying hydroxide compounds | Sachem, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5709790-A | Electrochemical process for purifying hydroxide compounds | SACHEM, INC. (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0652041-A2 | Method for producing high purity hydroxides and alkoxides | Sachem, Inc. (US) | 1995-05-10 | — | — | EP | disclosed |
| US-5389211-A | Method for producing high purity hydroxides and alkoxides | SACHEM, INC. (US) | 1995-02-14 | — | — | US | disclosed |