Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28249742 | 0.87 | EPHX2 (0.56) | ALDH1A1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL1424816 | 0.79 | DRD4 (0.83) | RECQLALDH1A1KMT2ADRD2DRD4 | |
| SCHEMBL28249698 | 0.79 | DRD2 (0.45) | ALDH1A1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL28249025 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL31616382 | 0.75 | CCR3 (0.74) | RECQLALDH1A1KMT2ADRD2DRD4 | |
| SCHEMBL31616363 | 0.75 | CCR3 (0.74) | RECQLALDH1A1KMT2ADRD2DRD4 | |
| SCHEMBL5429317 | 0.74 | MEN1 (0.55) | ALDH1A1KMT2ADRD2DRD3POLB | |
| SCHEMBL3960592 | 0.73 | EPHX2 (0.72) | RECQLALDH1A1KMT2AEPHX2RAB9A | |
| SCHEMBL11417263 | 0.72 | RAB9A (0.84) | RECQLALDH1A1KMT2AEPHX2RAB9A | |
| SCHEMBL13200773 | 0.72 | RECQL (0.73) | RECQLALDH1A1KMT2AEPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658897-A | Acetobenzylamide piperazine（Pyridine）Analog derivative and its application as neuroprotection agent | 上海医药工业研究院 | 2018-10-16 | — | — | CN | claimed |