Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.55 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391221 | 0.80 | DPP8 (0.62) | MEN1KMT2AATMCACNA1BCACNA2D1 | |
| SCHEMBL7391223 | 0.80 | DPP8 (0.62) | MEN1KMT2AATMCACNA1BCACNA2D1 | |
| SCHEMBL12487367 | 0.79 | RAB9A (0.59) | MEN1KMT2ARAB9APLAUPLAUR | |
| SCHEMBL6192045 | 0.78 | RAB9A (0.62) | MEN1KMT2ARAB9APLAUPLAUR | |
| SCHEMBL5321539 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2AATMPLAUPLAUR | |
| SCHEMBL11251072 | 0.75 | SLC6A4 (0.55) | RAB9AOPRD1PLAUPLAURLMNA | |
| SCHEMBL4776945 | 0.75 | DPP8 (0.59) | MEN1KMT2AATMCACNA1BCACNA2D1 | |
| SCHEMBL5322283 | 0.75 | MAOB (0.55) | MEN1KMT2APLAUPLAURLMNA | |
| SCHEMBL2293693 | 0.74 | CACNA1C (0.69) | MEN1KMT2AATMCACNA1BCACNA2D1 | |
| SCHEMBL28249019 | 0.74 | RECQL (0.55) | MEN1KMT2ARAB9AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096251-A1 | INHIBITORS OF CPT IN THE CENTRAL NERVOUS SYSTEM AS ANTIDIABETIC AND/OR ANTI-OBESITY DRUGS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096251-A1 | INHIBITORS OF CPT IN THE CENTRAL NERVOUS SYSTEM AS ANTIDIABETIC AND/OR ANTI-OBESITY DRUGS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-08-30 | — | — | WO | disclosed |