Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775058 | 0.88 | TSHR (0.48) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL10697123 | 0.78 | SLC6A3 (0.41) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL28072858 | 0.78 | TSHR (0.46) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL776890 | 0.75 | TSHR (0.48) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL3882388 | 0.74 | SLC6A3 (0.42) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL3956655 | 0.73 | TSHR (0.46) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL23713651 | 0.71 | TSHR (0.44) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8813043 | 0.71 | TSHR (0.44) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL4976471 | 0.71 | TSHR (0.50) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL5330618 | 0.71 | TSHR (0.44) | TSHRSLC6A3CYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108887282-A | A kind of composition and preparation method thereof for preventing and treating yellow twig | 邓方坤 | 2018-11-27 | — | — | CN | disclosed |