SCHEMBL28249642

SCHEMBL28249642

C#CC(OCCCO)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.35
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 1/20 0.35
PTPN1 P18031 1/20 0.34
RECQL P46063 1/20 0.33
GSR P00390 1/20 0.33
KDM4E B2RXH2 2/20 0.33
TSHR P16473 2/20 0.32
GAA P10253 1/20 0.32
NPBWR1 P48145 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MCHR1 Q99705 1/20 0.32
SCN1A P35498 3/20 0.32
SCN2A Q99250 3/20 0.32
SCN3A Q9NY46 3/20 0.32
KCNH2 Q12809 2/20 0.32
HRH4 Q9H3N8 2/20 0.32
TRPA1 O75762 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28249640 1.00 LMNA (0.35) LMNAALDH1A1HSD17B10PTPN1RECQL
SCHEMBL28865641 0.89 ALDH1A1 (0.39) LMNAALDH1A1RECQLGSRKDM4E
SCHEMBL25207508 0.89 ALDH1A1 (0.39) LMNAALDH1A1RECQLGSRKDM4E
SCHEMBL15483258 0.83 LTA4H (0.41) LMNATSHRGAAKMT2ASCN1A
SCHEMBL4667514 0.76 SCN1A (0.53) LMNAHSD17B10KDM4ETSHRSCN1A
SCHEMBL28249629 0.76 POLB (0.37) LMNAALDH1A1KDM4ETSHRKMT2A
SCHEMBL28249639 0.76 POLB (0.37) LMNAALDH1A1KDM4ETSHRKMT2A
SCHEMBL28249637 0.76 POLB (0.37) LMNAALDH1A1KDM4ETSHRKMT2A
SCHEMBL28249627 0.76 POLB (0.37) LMNAALDH1A1KDM4ETSHRKMT2A
SCHEMBL28249626 0.76 POLB (0.37) LMNAALDH1A1KDM4ETSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108722484-B Composition for preparing propargyl ether 四川大学 2021-04-27 CN disclosed
CN-108722484-A A kind of composition preparing propargyl ether 四川大学 2018-11-02 CN disclosed