SCHEMBL28865641

SCHEMBL28865641

C#C[C@@H](OCCO)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
RECQL P46063 1/20 0.39
CYP2D6 P10635 3/20 0.37
SLC6A2 P23975 3/20 0.37
SLC6A4 P31645 3/20 0.37
SLC6A3 Q01959 3/20 0.37
KCNH2 Q12809 3/20 0.37
CYP3A4 P08684 2/20 0.37
TSHR P16473 3/20 0.37
GAA P10253 1/20 0.37
NPBWR1 P48145 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MCHR1 Q99705 1/20 0.37
GSR P00390 1/20 0.35
GLS O94925 1/20 0.35
LMNA P02545 3/20 0.34
ADRA2A P08913 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ADRA2C P18825 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25207508 1.00 ALDH1A1 (0.39) ALDH1A1RECQLCYP2D6SLC6A2SLC6A4
SCHEMBL28249642 0.89 LMNA (0.35) ALDH1A1RECQLCYP2D6SLC6A2SLC6A4
SCHEMBL28249640 0.89 LMNA (0.35) ALDH1A1RECQLCYP2D6SLC6A2SLC6A4
SCHEMBL28249646 0.82 SLC6A3 (0.36) ALDH1A1SLC6A2SLC6A4SLC6A3NPSR1
SCHEMBL28865707 0.82 PYCR1 (0.36) SLC6A2SLC6A4SLC6A3NPSR1LMNA
SCHEMBL28865706 0.82 PYCR1 (0.36) SLC6A2SLC6A4SLC6A3NPSR1LMNA
SCHEMBL28249648 0.82 SLC6A3 (0.36) ALDH1A1SLC6A2SLC6A4SLC6A3NPSR1
SCHEMBL28250346 0.82 ADRB2 (0.38) ALDH1A1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL28250348 0.82 ADRB2 (0.38) ALDH1A1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL28938736 0.81 ALDH1A1 (0.39) ALDH1A1RECQLCYP2D6SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108722484-B Composition for preparing propargyl ether 四川大学 2021-04-27 CN disclosed
CN-108722484-A A kind of composition preparing propargyl ether 四川大学 2018-11-02 CN disclosed