Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.52 |
| ▸ | CETP | P11597 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250047 | 0.88 | NPC1 (0.57) | KCNK3LMNAP2RX1MRGPRX4CES2 | |
| SCHEMBL28250048 | 0.87 | RAB9A (0.51) | KCNK3LMNAP2RX1CES2MAPT | |
| SCHEMBL28250190 | 0.85 | POLB (0.54) | LMNANPSR1POLBALDH1A1NPC1 | |
| SCHEMBL28531213 | 0.83 | NPC1 (0.50) | KCNK3POLBNPC1RAB9AGPR132 | |
| SCHEMBL28525768 | 0.81 | NPC1 (0.57) | KCNK3LMNANPSR1HTTCES2 | |
| SCHEMBL5311319 | 0.80 | KIF11 (0.51) | MAPTNPC1RAB9A | |
| SCHEMBL25191493 | 0.79 | NPSR1 (0.60) | KCNK3LMNAP2RX1NPSR1MRGPRX4 | |
| SCHEMBL28546278 | 0.79 | GPR132 (0.46) | L3MBTL1POLBKAT6AALDH1A1MAPT | |
| SCHEMBL28528461 | 0.79 | POLB (0.50) | NPSR1HTTL3MBTL1GAACES2 | |
| SCHEMBL25400472 | 0.79 | RXFP1 (0.49) | LMNAP2RX1CETPNPSR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752232-B | Synthetic method of alpha-quaternary carbon amino acid | 四川大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-108752232-A | A kind of synthetic method of α-quaternary carbon amino acid | 四川大学 | 2018-11-06 | — | — | CN | disclosed |