Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250860 | 0.83 | KDM4E (0.55) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL4660910 | 0.81 | KMT2A (0.47) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL28865681 | 0.79 | EPHX2 (0.42) | LIPESMN1; SMN2SERPINE1ALDH1A1GPBAR1 | |
| SCHEMBL10964398 | 0.77 | CES2 (0.46) | RAB9ANPC1TLR7FAAHEPHX2 | |
| SCHEMBL28186416 | 0.76 | EPHX2 (0.49) | RAB9ANPC1SERPINE1KMT2AALDH1A1 | |
| SCHEMBL1875890 | 0.75 | SERPINE1 (0.49) | LIPESERPINE1KMT2AGPBAR1SLC6A2 | |
| SCHEMBL5649783 | 0.74 | RAB9A (0.62) | LIPERAB9ASMN1; SMN2NPC1SERPINE1 | |
| SCHEMBL15504635 | 0.71 | MAPT (0.57) | LIPERAB9ASMN1; SMN2SERPINE1NR1H3 | |
| SCHEMBL4602009 | 0.71 | ELANE (0.56) | RAB9ANPC1ALDH1A1TLR7FAAH | |
| SCHEMBL28580530 | 0.71 | GRIN2B (0.50) | RAB9ASMN1; SMN2MEN1KMT2ATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752258-A | Nickel is catalyzed Synthesis of Indole ketones derivant | 南开大学 | 2018-11-06 | — | — | CN | disclosed |