SCHEMBL6596574

SCHEMBL6596574

CCCOC(=O)c1ccccc1CCl

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.71
TSHR P16473 7/20 0.57
TDP1 Q9NUW8 4/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
CYP3A4 P08684 2/20 0.56
MAPK1 P28482 2/20 0.56
TP53 P04637 1/20 0.56
LMNA P02545 2/20 0.54
HSD17B10 Q99714 3/20 0.50
SCN1A P35498 2/20 0.48
SCN2A Q99250 2/20 0.48
SCN3A Q9NY46 2/20 0.48
KDM4E B2RXH2 3/20 0.48
POLB P06746 1/20 0.48
MAOB P27338 1/20 0.47
PDK2 Q15119 1/20 0.45
ESR1 P03372 1/20 0.45
CHRM1 P11229 1/20 0.45
SLC6A2 P23975 1/20 0.45
KDR P35968 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5679381 0.90 TSHR (0.73) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL8459868 0.89 TSHR (0.73) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL9279757 0.88 ALDH1A1 (0.79) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL7944766 0.86 ALDH1A1 (0.50) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL2825239 0.86 TSHR (0.69) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL8477782 0.85 ALDH1A1 (0.73) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL8477780 0.85 ALDH1A1 (0.73) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL6545714 0.85 ALDH1A1 (0.73) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL5597695 0.84 ALDH1A1 (0.53) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL19066309 0.84 ALDH1A1 (1.00) ALDH1A1TSHRTDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106062261-B Crimped fiber and nonwoven fabric 出光兴产株式会社 2019-07-23 CN disclosed
CN-106661792-B Spun-bonded nonwoven fabric and method for producing same 出光兴产株式会社 2019-06-21 CN disclosed
CN-105121729-B Nonwoven fabric and fiber product 出光兴产株式会社 2018-04-13 CN disclosed
CN-106661792-A Spun-bonded nonwoven fabric and method for producing same 出光兴产株式会社 2017-05-10 CN disclosed
CN-106062261-A Crimped fiber and nonwoven fabric 出光兴产株式会社 2016-10-26 CN disclosed
CN-105121729-A Nonwoven fabric and fiber product IDEMITSU KOSAN CO 2015-12-02 CN disclosed
CN-101688341-A Elastic nonwoven fabric, method for producing same, and fiber product using same IDEMITSU KOSAN CO 2010-03-31 CN disclosed
EP-0888338-B1 NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPAN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES AVENTIS PHARMA INC (US) 2004-11-17 EP disclosed
CN-1529728-A Mixtures containing 1,1,1,3,3-pentafluoropropane and 1,1,3,3-pentafluorobutane ����Τ�����ʹ�˾ 2004-09-15 CN disclosed
CN-1143856-C Novel substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) [1,4] diazepan-1-yl)-1-(aryl) butyl) benzamides useful for treatment of allergic diseases ���µ�˹ҩ�﹫˾ 2004-03-31 CN disclosed
US-5618969-A Intermediates for imidazopyridines EISAI CO., LTD. (JP) 1997-04-08 US disclosed
US-5608068-A Process for the preparation of imidazopyridine derivatives and intermediates EISAI CO., LTD. (JP) 1997-03-04 US disclosed
US-5587504-A Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates EISAI CO., LTD. (JP) 1996-12-24 US disclosed
US-5583229-A Process for the preparation of imidazopyridine derivatives EISAI CO., LTD. (JP) 1996-12-10 US disclosed
US-5559236-A Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists EISAI CO., LTD. (JP) 1996-09-24 US disclosed
US-5557002-A Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists EISAI CO., LTD. (JP) 1996-09-17 US disclosed
US-5554757-A Process for the preparation of imidazopyridine derivatives, and intermediates therefore EISAI CO., LTD. (JP) 1996-09-10 US disclosed
EP-0627433-A1 PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE Eisai Co., Ltd. (JP) 1994-12-07 EP disclosed
US-4066435-A BENZYL TRIALKYL PHOSPHONIUM HALIDE MONSANTO COMPANY (US) 1978-01-03 US disclosed
US-4053501-A PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1977-10-11 US disclosed